Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.55 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435644 | 1.00 | ITGB3 (0.55) | ITGB3ITGA2BSMYD3DPP4HRH2 | |
| Hydrochloric Acid SCHEMBL6438357 | 0.98 | ITGB3 (0.54) | ITGB3ITGA2BSMYD3DPP4HRH2 | |
| Hydrochloric Acid SCHEMBL6438352 | 0.98 | ITGB3 (0.54) | ITGB3ITGA2BSMYD3DPP4HRH2 | |
| SCHEMBL8381226 | 0.85 | ITGB3 (0.50) | ITGB3ITGA2BDPP4HRH2HRH1 | |
| SCHEMBL8381227 | 0.85 | ITGB3 (0.50) | ITGB3ITGA2BDPP4HRH2HRH1 | |
| SCHEMBL8379156 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BSMYD3DPP4HRH2 | |
| SCHEMBL15045202 | 0.81 | GPR119 (0.40) | ITGB3ITGA2BSMYD3DPP4HRH2 | |
| Trifluoroacetic Acid SCHEMBL8481776 | 0.80 | DPP7 (0.43) | ITGB3ITGA2BSMYD3DPP4 | |
| SCHEMBL8880829 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BHRH2HRH1 | |
| SCHEMBL24271978 | 0.78 | ITGB3 (0.45) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505062-A1 | Heterocyclic derivatives and their use as antithrombotic agents | Akzo Nobel N.V. (NL) | 2005-02-09 | — | — | EP | disclosed |
| EP-0975600-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | Akzo Nobel N.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998047876-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | AKZO NOBEL N.V. (NL) | 1998-10-29 | — | — | WO | disclosed |
| US-5747522-A | ANTICOAGULANTS; ANTIINFLAMMATORY AGENTS; ANTITUMOR AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1998-05-05 | — | — | US | disclosed |
| US-5670515-A | TREATMENT OF THROMBOSIS, STROKE, CARDIAC INFARCT, INFLAMMATION, AND ARTERIOSCLEROSIS; ANTITUMOR AGENTS, WOUND HEALING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1997-09-23 | — | — | US | disclosed |