Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 6/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435636 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2BSMYD3DPP4HRH2 | |
| SCHEMBL6435644 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2BSMYD3DPP4HRH2 | |
| Hydrochloric Acid SCHEMBL6438357 | 0.80 | ITGB3 (0.54) | ITGB3ITGA2BSMYD3DPP4HRH2 | |
| Hydrochloric Acid SCHEMBL6438352 | 0.80 | ITGB3 (0.54) | ITGB3ITGA2BSMYD3DPP4HRH2 | |
| SCHEMBL15045201 | 0.78 | DPP4 (0.49) | SMYD3DPP4DPP7HRH3MEN1 | |
| SCHEMBL13162313 | 0.78 | GPR119 (0.36) | GPR119ITGB3ITGA2B | |
| SCHEMBL19023658 | 0.76 | LPL (0.39) | GPR119ITGB3ITGA2B | |
| SCHEMBL8379156 | 0.76 | ITGB3 (0.42) | ITGB3ITGA2BSMYD3DPP4HRH2 | |
| SCHEMBL8690808 | 0.76 | MEN1 (0.40) | SMYD3DPP4DPP7MEN1ALDH1A1 | |
| SCHEMBL8690804 | 0.73 | SMYD3 (0.38) | SMYD3DPP4DPP7HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604601-A1 | HETERO RING COMPOUND | Astellas Pharma Inc. (JP) | 2013-06-19 | — | — | EP | disclosed |