Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436802 | 0.87 | MAPT (0.44) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL6431994 | 0.85 | GAA (0.46) | MAPTSMN1; SMN2TP53GAARECQL | |
| SCHEMBL6439454 | 0.84 | GAA (0.45) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL6416982 | 0.78 | MAPT (0.45) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL3054070 | 0.78 | MAPT (0.39) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL3060981 | 0.78 | MAPT (0.44) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL6432336 | 0.76 | SMN1; SMN2 (0.37) | MAPTSMN1; SMN2TP53GAARECQL | |
| SCHEMBL3054066 | 0.74 | MAPT (0.43) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL3051396 | 0.73 | TP53 (0.55) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL3052187 | 0.72 | HTT (0.57) | MAPTSMN1; SMN2TP53CCR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044270-A1 | OXADIAZOLOPYRAZINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS | 4SC AG (DE) | 2005-05-19 | — | — | WO | disclosed |