SCHEMBL6435930

SCHEMBL6435930

c1ccc([N]c2ccc3ccccc3c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 2/20 0.52
HTR3B O95264 2/20 0.52
HTR3A P46098 2/20 0.52
HTR3D Q70Z44 2/20 0.52
HTR3C Q8WXA8 2/20 0.52
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
HSP90AA1 P07900 3/20 0.50
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
SIGMAR1 Q99720 1/20 0.42
CYP2A6 P11509 5/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL715672 1.00 HTR3E (0.52) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL1354442 0.93 HTR3E (0.58) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL6542062 0.85 HTR3E (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL6542073 0.85 HTR3E (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL6541318 0.85 HTR3E (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL6422598 0.81 CYP2A6 (0.54) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10349716 0.81 MEN1 (0.73) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL2291265 0.81 MEN1 (0.73) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10017620 0.77 MEN1 (0.75) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL3283287 0.77 MEN1 (0.75) HTR3EHTR3BHTR3AHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10069075-B2 Charge-transporting varnish NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-09-04 US claimed
US-20160005975-A1 CHARGE-TRANSPORTING VARNISH NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-01-07 US claimed
EP-2963699-A1 CHARGE-TRANSPORTING VARNISH Nissan Chemical Industries, Ltd. (JP) 2016-01-06 EP claimed
EP-1379534-B1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS (DE) 2004-12-15 EP claimed
EP-1379534-A1 RHODIUM AND IRIDIUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2004-01-14 EP claimed
EP-1294695-A2 SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS Ortho-McNeil Pharmaceutical, Inc. (US) 2003-03-26 EP claimed
WO-2002081488-A1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2002-10-17 WO claimed
WO-2001085694-A2 SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-11-15 WO claimed
CN-110246870-B Display device 索尼公司 2023-06-02 CN disclosed
CN-110085633-B Display device 索尼公司 2023-05-30 CN disclosed
CN-105374850-B Display device 索尼公司 2020-03-17 CN disclosed
US-10069075-B2 Charge-transporting varnish NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-09-04 US disclosed
US-10069075-B2 Charge-transporting varnish NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-09-04 US disclosed
CN-103035665-B Display of organic electroluminescence 株式会社日本有机雷特显示器 2016-08-10 CN disclosed
US-6461538-B2 Production process for indolizine compounds and their use in organic light-emitting devices FUJI PHOTO FILM CO., LTD. (JP) 2002-10-08 US disclosed
WO-2001085694-A2 SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-11-15 WO disclosed
US-20010015614-A1 Novel indolizine compound, production process for novel indolizine compound, organic light-emitting device material having indolizine skeleton, and organic light-emitting device using these UDC IRELAND LIMITED (IE) 2001-08-23 US disclosed
US-6277907-B1 STABILIZING THERMOPLASTIC RESINS AGAINST OXIDATIVE DEGRADATION UNIROYAL CHEMICAL COMPANY, INC. 2001-08-21 US disclosed
US-4229325-A VULCANIZABLE COPOLYMERS OR TERPOLYMERS, A SULFUR DONOR, A DELAYED ACTION ACCELERATOR; GEL-FREE EXXON RESEARCH & ENGINEERING CO. (US) 1980-10-21 US disclosed
US-4151343-A High unsaturation butyl rubbers EXXON RESEARCH & ENGINEERING CO. (US) 1979-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010015614-A1 Novel indolizine compound, production process for novel indolizine compound, organic light-emitting device material having indolizine skeleton, and organic light-emitting device using these INMT, IDO1, INTS9 HTR3E 104/4885HTR3B 202/4885HTR3A 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.