SCHEMBL715672

SCHEMBL715672

c1ccc([N]c2ccc3ccccc3c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 2/20 0.52
HTR3B O95264 2/20 0.52
HTR3A P46098 2/20 0.52
HTR3D Q70Z44 2/20 0.52
HTR3C Q8WXA8 2/20 0.52
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
HSP90AA1 P07900 3/20 0.50
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
SIGMAR1 Q99720 1/20 0.42
CYP2A6 P11509 5/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6435930 1.00 HTR3E (0.52) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL1354442 0.93 HTR3E (0.58) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL6542062 0.85 HTR3E (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL6542073 0.85 HTR3E (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL6541318 0.85 HTR3E (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL6422598 0.81 CYP2A6 (0.54) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10349716 0.81 MEN1 (0.73) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL2291265 0.81 MEN1 (0.73) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10017620 0.77 MEN1 (0.75) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL3283287 0.77 MEN1 (0.75) HTR3EHTR3BHTR3AHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10069075-B2 Charge-transporting varnish NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-09-04 US claimed
US-20160005975-A1 CHARGE-TRANSPORTING VARNISH NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-01-07 US claimed
EP-2963699-A1 CHARGE-TRANSPORTING VARNISH Nissan Chemical Industries, Ltd. (JP) 2016-01-06 EP claimed
US-7534853-B2 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2009-05-19 US claimed
US-20080220286-A1 Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films TSINGHUA UNIVERSITY (CN) 2008-09-11 US claimed
CN-100357388-C Organic electroluminescent compositions 3M INNOVATIVE PROPERTIES CO (US) 2007-12-26 CN claimed
US-7094897-B2 Rhodium and iridium complexes COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2006-08-22 US claimed
US-20060065890-A1 Rhodium and iridium complexes COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2006-03-30 US claimed
CN-1681903-A organic electroluminescent composition 3M INNOVATIVE PROPERTIES CO (US) 2005-10-12 CN claimed
EP-1554360-A2 ORGANIC ELECTROLUMINESCENT COMPOSITIONS 3M Innovative Properties Company (US) 2005-07-20 EP claimed
EP-1379534-B1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS (DE) 2004-12-15 EP claimed
WO-2004099338-A2 ORGANIC ELECTROLUMINESCENT COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-11-18 WO claimed
US-20040133004-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-08 US claimed
US-20040062947-A1 Organic electroluminescent compositions 3M INNOVATIVE PROPERTIES COMPANY 2004-04-01 US claimed
US-6346621-B1 INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN TOSOH CORPORATION (JP) 2002-02-12 US claimed
EP-4365180-A1 RARE EARTH COMPLEX Tosoh Corporation (JP) 2024-05-08 EP disclosed
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN disclosed
US-5624935-A ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS SANKYO COMPANY, LIMITED 1997-04-29 US disclosed
CN-1118781-A Heterocyclic compound with activity against diabetes and preparation and application of same MITSUTAKA CO LTD (JP) 1996-03-20 CN disclosed
EP-0676398-A2 Heterocyclic compounds having anti-diabetic activity, their preparation and their use SANKYO COMPANY LIMITED (JP) 1995-10-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060065890-A1 Rhodium and iridium complexes RPIA, INPP5B, SIRT5 HTR3E 4257/4885HTR3B 4649/4885HTR3A 4643/4885
US-20080220286-A1 Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films EED, DDT, RABL6 HTR3E 1478/4885HTR3B 2809/4885HTR3A 3048/4885
US-20040133004-A1 Rhodium and iridium complexes RPIA, SIRT5, INPP5B HTR3E 4196/4885HTR3B 4607/4885HTR3A 4634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.