Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643705 | 0.83 | POLB (0.44) | PPARAPPARGPOLBCA12CA1 | |
| SCHEMBL642802 | 0.82 | CA12 (0.47) | PPARAPPARGPOLBCA12CA1 | |
| SCHEMBL641567 | 0.80 | POLB (0.54) | PPARAPPARGPOLBCA12CA1 | |
| SCHEMBL642836 | 0.78 | POLB (0.43) | PPARAPPARGPOLBCA12CA1 | |
| SCHEMBL10091826 | 0.78 | PPARA (0.42) | PPARAPPARGPOLBLMNAHPGD | |
| SCHEMBL21711828 | 0.75 | CA12 (0.42) | PPARAPPARGPOLBCA12CA1 | |
| SCHEMBL641854 | 0.74 | CA12 (0.43) | PPARAPPARGPOLBCA12CA1 | |
| SCHEMBL21711899 | 0.70 | PPARA (0.44) | PPARAPPARGPOLBCA12CA1 | |
| SCHEMBL11065495 | 0.69 | PPARA (0.49) | PPARAPPARGPOLBCA12CA1 | |
| SCHEMBL1739400 | 0.68 | CA1 (0.54) | PPARAPOLBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074101-B1 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2012-08-08 | — | — | EP | disclosed |
| US-8119422-B2 | Stable acridinium esters with fast light emission | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100099077-A1 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-04-22 | — | — | US | disclosed |
| EP-2074101-A2 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | Siemens Healthcare Diagnostics Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008067055-A2 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099077-A1 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | ACR, NAALAD2, CES2 | PPARA 2978/4885PPARG 2873/4885POLB 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.