Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643705 | 0.91 | POLB (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21044158 | 0.80 | RAB9A (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21711899 | 0.79 | PPARA (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9492679 | 0.78 | CYP4F2 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1017686 | 0.76 | RAB9A (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3778844 | 0.75 | TOP1 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL641567 | 0.75 | POLB (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7954358 | 0.74 | CA1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18573170 | 0.74 | POLB (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL643606 | 0.74 | PPARA (0.41) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074101-B1 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2012-08-08 | — | — | EP | disclosed |
| US-8119422-B2 | Stable acridinium esters with fast light emission | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100099077-A1 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-04-22 | — | — | US | disclosed |
| EP-2074101-A2 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | Siemens Healthcare Diagnostics Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008067055-A2 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099077-A1 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | ACR, NAALAD2, CES2 | CA12 1268/4885CA1 2968/4885CA2 2783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.