Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241423 | 0.87 | DNMT1 (0.51) | SMN1; SMN2NPC1KMT2AMEN1MAPT | |
| SCHEMBL3240191 | 0.82 | MMP9 (0.57) | SMN1; SMN2HTTNPC1KMT2AMEN1 | |
| SCHEMBL6439246 | 0.80 | RAB9A (0.56) | SMN1; SMN2NPC1KMT2AMEN1MAPT | |
| SCHEMBL14880166 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2HTTNPC1KMT2AMEN1 | |
| SCHEMBL6436343 | 0.76 | NPC1 (0.56) | SMN1; SMN2HTTNPC1KMT2AMEN1 | |
| SCHEMBL3237959 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTNPC1KMT2AMEN1 | |
| SCHEMBL5558427 | 0.72 | MMP9 (0.49) | SMN1; SMN2HTTNPC1KMT2AMEN1 | |
| SCHEMBL14992382 | 0.72 | HTT (0.73) | SMN1; SMN2HTTNPC1KMT2AMEN1 | |
| SCHEMBL15140299 | 0.71 | HTT (1.00) | SMN1; SMN2HTTNPC1KMT2AMEN1 | |
| SCHEMBL485711 | 0.71 | MEN1 (0.82) | SMN1; SMN2HTTNPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509516-A1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | Aventis Pharma Deutschland GmbH (DE) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003104221-A1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-18 | — | — | WO | disclosed |