Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.56 |
| ▸ | NPC1 | O15118 | 12/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241423 | 0.86 | DNMT1 (0.51) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL3238075 | 0.82 | MMP9 (0.56) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6436345 | 0.80 | SMN1; SMN2 (0.57) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL6439243 | 0.75 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL7718028 | 0.73 | NPC1 (0.72) | RAB9ANPC1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL18027795 | 0.73 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL3240104 | 0.70 | MMP9 (0.56) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5553523 | 0.70 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL12764166 | 0.70 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL27787262 | 0.69 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509516-A1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | Aventis Pharma Deutschland GmbH (DE) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003104221-A1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-18 | — | — | WO | disclosed |