Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698187 | 0.83 | MTOR (0.50) | NISCHMTORADKBTKTNKS | |
| SCHEMBL15826247 | 0.72 | BTK (0.51) | BTKAURKAAURKBINCENPALDH1A1 | |
| SCHEMBL3829512 | 0.71 | GAA (0.49) | PARP1ALDH1A1KDM4EGAA | |
| SCHEMBL10597323 | 0.71 | METAP2 (0.42) | NISCHMTORADKALDH1A1KDM4E | |
| SCHEMBL16631769 | 0.69 | DCUN1D1 (0.33) | NISCHMTORADKPARP1DAO | |
| SCHEMBL18081960 | 0.69 | RAB9A (0.40) | TNKSTNKS2PARP1ALDH1A1KDM4E | |
| SCHEMBL745730 | 0.69 | IDO1 (0.41) | BTKPARP1ALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL6225223 | 0.68 | IDO1 (0.40) | BTKALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL16631462 | 0.67 | SMN1; SMN2 (0.36) | NISCHMTORADKDAOALDH1A1 | |
| SCHEMBL16631766 | 0.67 | NAPRT (0.49) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061421-A | Method for preparing 2-chloro-1, 8-naphthyridine derivative | UNIV CHINA PETROLEUM | 2015-11-18 | — | — | CN | claimed |
| CN-105061421-A | Method for preparing 2-chloro-1, 8-naphthyridine derivative | UNIV CHINA PETROLEUM | 2015-11-18 | — | — | CN | disclosed |
| CN-105061421-A | Method for preparing 2-chloro-1, 8-naphthyridine derivative | UNIV CHINA PETROLEUM | 2015-11-18 | — | — | CN | disclosed |
| EP-1561753-A2 | Benzo[b]chromenonapthyridin-7-one and pyrano[2',3':7,8]quino[2,3-b]Quinoxalin-7-one derivatives, process of synthesis, pharmaceutical compositions and their antitumoral properties for the treatment of cancer | Les Laboratoires Servier (FR) | 2005-08-10 | — | — | EP | disclosed |