Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.91 |
| ▸ | CA2 | P00918 | 5/20 | 0.91 |
| ▸ | CA4 | P22748 | 4/20 | 0.91 |
| ▸ | CA6 | P23280 | 4/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | HPGD | P15428 | 2/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.75 |
| ▸ | RECQL | P46063 | 2/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabromocatechol SCHEMBL29382370 | 0.95 | CA1 (1.00) | CA1CA2CA4CA6ALDH1A1 | |
| Tetrabromocatechol SCHEMBL985158 | 0.95 | CA1 (1.00) | CA1CA2CA4CA6ALDH1A1 | |
| Pentabromophenol SCHEMBL268325 | 0.86 | ALOX15 (1.00) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL18733082 | 0.86 | CA1 (0.67) | CA1CA2CA4CA6ALDH1A1 | |
| Tetrabromocatechol SCHEMBL27576909 | 0.84 | CA1 (0.77) | CA1CA2CA4CA6ALDH1A1 | |
| Pentabromophenol SCHEMBL11697558 | 0.82 | ALOX15 (0.91) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL127379 | 0.82 | ALOX15 (0.91) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL48572 | 0.80 | ALDH1A1 (0.90) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL24727403 | 0.75 | CA1 (0.53) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL8953674 | 0.75 | CA1 (0.64) | CA1CA2CA4CA6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009729-B1 | HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM | MINNESOTA MINING & MFG (US) | 2005-01-19 | — | — | EP | disclosed |
| US-6362379-B2 | ACRYLATES HAVING HIGH DEGREE OF HALOGENATION AND POLYMERS USING THESE MONOMERS; USEFUL FOR OPTICAL WAVEGUIDES AND TELECOMMUNICATION | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6313245-B1 | USED IN OPTICAL DEVICES INCLUDING OPTICAL WAVEGUIDES AND INTERCONNECTING DEVICES | 3M INNOVATIVE PROPERTIES COMPANY | 2001-11-06 | — | — | US | disclosed |
| US-20010037028-A1 | Halogenated acrylates and polymers derived therefrom | 3M INNOVATIVE PROPERTIES COMPANY | 2001-11-01 | — | — | US | disclosed |
| US-6288266-B1 | HALOGENATED ACRYLATES OR THIOACRYLATES FOR POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY | 2001-09-11 | — | — | US | disclosed |
| CN-1259932-A | Halogenated acrylates and polymers derived therefrom | MINNESOTA MINING & MFG (US) | 2000-07-12 | — | — | CN | disclosed |
| EP-1009729-A1 | HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| US-6005137-A | POLYMERS USED IN OPTICAL DEVICES INCLUDING OPTICAL WAVEGUIDES AND INTERCONNECTING DEVICES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| WO-1998056749-A1 | HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010037028-A1 | Halogenated acrylates and polymers derived therefrom | ZYX, ACR, ORMDL3 | CA1 4704/4885CA2 4722/4885CA4 3186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.