Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.49 |
| ▸ | F2 | P00734 | 6/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6432605 | 0.85 | F10 (0.50) | F10F2 | |
| SCHEMBL6432401 | 0.83 | F10 (0.50) | F10F2FOLH1RAB9A | |
| SCHEMBL6437281 | 0.79 | F10 (0.48) | F10F2FOLH1RAB9A | |
| SCHEMBL6436689 | 0.75 | F10 (0.51) | F10F2 | |
| SCHEMBL6432609 | 0.75 | F10 (0.47) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL6436682 | 0.75 | F10 (0.84) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL6432601 | 0.74 | F10 (0.77) | F10F2 | |
| SCHEMBL6437263 | 0.67 | F10 (0.61) | F10F2 | |
| SCHEMBL6439394 | 0.67 | F10 (0.60) | F10F2 | |
| SCHEMBL6435208 | 0.67 | F10 (0.71) | F10F2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |