SCHEMBL643670

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL643598	0.84	ALDH1A1 (0.46)	MEN1KMT2ARAB9ATSHRMAPT
	SCHEMBL12035641	0.83	LMNA (0.38)	MEN1KMT2ARAB9ATSHRMAPT
	SCHEMBL12035940	0.83	FFAR4 (0.43)	RAB9ATSHRMAPTLMNASMN1; SMN2
	SCHEMBL643419	0.80	S1PR2 (0.37)	RAB9ATSHRMAPTLMNASMN1; SMN2
	SCHEMBL12036049	0.77	LMNA (0.39)	KMT2ARAB9AMAPTLMNANPSR1
	SCHEMBL2436137	0.77	ALOX5 (0.46)	TSHRLMNANPSR1KDM4EPOLB
	SCHEMBL643701	0.75	ALDH1A1 (0.38)	MEN1KMT2ARAB9ATSHRMAPT
	SCHEMBL642200	0.74	MAPT (0.41)	MEN1KMT2ARAB9ATSHRMAPT
	SCHEMBL10860141	0.72	MAPT (0.39)	RAB9ATSHRMAPTLMNASMN1; SMN2
	SCHEMBL642957	0.72	LMNA (0.49)	MEN1KMT2ARAB9ATSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.