SCHEMBL6436870

SCHEMBL6436870

CC(O)Cc1ccc(C(C)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.48
ESR2 Q92731 2/20 0.48
PTGS1 P23219 4/20 0.44
PTGS2 P35354 4/20 0.44
LMNA P02545 2/20 0.44
CYP2C9 P11712 2/20 0.44
AKR1C3 P42330 2/20 0.44
CXCR1 P25024 2/20 0.44
CXCR2 P25025 2/20 0.44
ALB P02768 1/20 0.44
ALOX5 P09917 1/20 0.44
RARB P10826 1/20 0.44
ADRB3 P13945 1/20 0.44
NFKB1 P19838 1/20 0.44
HTR2A P28223 1/20 0.44
NR1I3 Q14994 1/20 0.44
SLC22A6 Q4U2R8 1/20 0.44
CXCL8 P10145 1/20 0.44
TSHR P16473 1/20 0.44
AKR1C2 P52895 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196800 0.87 TAAR1 (0.48) ESR1ESR2PTGS1PTGS2LMNA
SCHEMBL9118030 0.86 PTGS1 (0.59) ESR1PTGS1PTGS2LMNACYP2C9
SCHEMBL8559655 0.86 PTGS1 (0.59) ESR1PTGS1PTGS2LMNACYP2C9
SCHEMBL3371824 0.86 ESR1 (0.48) ESR1ESR2PTGS1PTGS2LMNA
SCHEMBL4049764 0.86 PTGS1 (0.59) ESR1PTGS1PTGS2LMNACYP2C9
SCHEMBL3193540 0.84 ESR1 (0.47) ESR1ESR2PTGS1PTGS2LMNA
SCHEMBL6446365 0.80 ESR1 (0.46) ESR1ESR2PTGS1PTGS2LMNA
SCHEMBL9175435 0.80 IDO1 (0.44) ESR1ESR2PTGS1PTGS2LMNA
SCHEMBL1336531 0.80 ALDH1A1 (0.46) ESR1ESR2PTGS1LMNAADRB3
SCHEMBL7611040 0.80 ESR1 (0.43) ESR1ESR2PTGS1PTGS2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0473163-B1 Liquid composition which can polymerize into almost colourless and easily dyeable organic glass GREAT LAKES CHEMICAL ITALIA (IT) 1995-11-02 EP claimed
US-5196492-A Aliphatic polyol reduces coloring, colorless and dyeable, ophthalmic lenses ENICHEM SYNTHESIS S.P.A. (IT) 1993-03-23 US claimed
EP-0473163-A1 Liquid composition which can polymerize into almost colourless and easily dyeable organic glass GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) 1992-03-04 EP claimed
EP-4619448-A1 COMPOSITION BASED ON ALLYL MONOMERS AND ON PEROXIDE, FOR THE MANUFACTURE OF ORGANIC GLASSES ARKEMA France (FR) 2025-09-24 EP disclosed
WO-2024105341-A1 COMPOSITION BASED ON ALLYL MONOMERS AND ON PEROXIDE, FOR THE MANUFACTURE OF ORGANIC GLASSES ARKEMA FRANCE (FR) 2024-05-23 WO disclosed
EP-3448893-B1 COMPOSITION BASED ON ALLYL MONOMERS AND PEROXIDE(S) FOR THE MANUFACTURE OF ORGANIC GLASSES ARKEMA FRANCE (FR) 2024-05-22 EP disclosed
US-10851222-B2 Composition based on allyl monomers and peroxide(s) for the manufacture of organic glasses ARKEMA FRANCE (FR) 2020-12-01 US disclosed
US-20200062924-A1 COMPOSITION BASED ON ALLYL MONOMERS AND PEROXIDE(S) FOR THE MANUFACTURE OF ORGANIC GLASSES ARKEMA FRANCE (FR) 2020-02-27 US disclosed
EP-1023618-B1 OPHTHALMIC LENSES GREAT LAKES CHEMICAL CORP (US) 2005-05-18 EP disclosed
US-6673276-B1 OLYMERIZING A POLYMERIZABLE COMPOSITION IN THE PRESENCE OF A MOULD RELEASE AGENT SUCH AS METAL ORGANIC COMPOUND, A METAL ORGANIC COMPLEX, AND A SALT THEREOF TO PREVENT FERN FORMATION GREAT LAKES CHEMICAL CORPORATION 2004-01-06 US disclosed
EP-1077797-B1 OPHTHALMIC LENSES GREAT LAKES CHEMICAL CORP (US) 2003-03-26 EP disclosed
US-5992997-A REFRACTIVE INDEX FROM 1.498 TO 1.505, WHICH ARE THE CURED PRODUCT OF A POLY(ALLYL CARBONATE) OF A POLYHYDROXY ALCOHOL AND A DIALLYL PHTHALATE TYPE OLIGOMER AKZO NOBEL NV (NL) 1999-11-30 US disclosed
EP-0715725-B1 OPHTHALMIC LENSES AKZO NOBEL NV (NL) 1998-02-04 EP disclosed
EP-0808469-A1 OPHTHALMIC LENSES Akzo Nobel N.V. (NL) 1997-11-26 EP disclosed
US-5663279-A CURED ALLYL MODIFIED POLYESTERS OR POLYCARBONATES FOR LENSES AKZO NOBEL NV (NL) 1997-09-02 US disclosed
WO-1996024865-A1 OPHTHALMIC LENSES AKZO NOBEL N.V. (NL) 1996-08-15 WO disclosed
EP-0715725-A1 OPHTHALMIC LENSES Akzo Nobel N.V. (NL) 1996-06-12 EP disclosed
EP-0473163-B1 Liquid composition which can polymerize into almost colourless and easily dyeable organic glass GREAT LAKES CHEMICAL ITALIA (IT) 1995-11-02 EP disclosed
WO-1995006266-A1 OPHTHALMIC LENSES AKZO NOBEL N.V. (NL) 1995-03-02 WO disclosed
EP-0473163-A1 Liquid composition which can polymerize into almost colourless and easily dyeable organic glass GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) 1992-03-04 EP disclosed