Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.59 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.59 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 1/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118030 | 1.00 | PTGS1 (0.59) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL8559655 | 1.00 | PTGS1 (0.59) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL6436870 | 0.86 | ESR1 (0.48) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL12030802 | 0.86 | PTGS1 (0.59) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL9340078 | 0.86 | PTGS1 (0.59) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL23634205 | 0.82 | PTGS1 (0.55) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL13993311 | 0.82 | PTGS1 (0.55) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL28533038 | 0.82 | PTGS1 (0.55) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| Hydrogen Peroxide SCHEMBL9581174 | 0.82 | PTGS1 (0.64) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL1131597 | 0.82 | PTGS1 (0.56) | PTGS1PTGS2CXCR1CXCR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12378174-B2 | Process for producing 1-(4-isobutylphenyl)ethanol by hydrogenation of 1-(4-isobutyl-phenyl)ethanone in the presence of a catalyst composition comprising copper | BASF SE (DE) | 2025-08-05 | — | — | US | claimed |
| EP-3891115-B1 | PROCESS FOR PRODUCING 1-(4-ISOBUTYLPHENYL)ETHANOL BY HYDROGENATION OF 1-(4-ISOBUTYL-PHENYL)ETHANONE IN THE PRESENCE OF A CATALYST COMPOSITION COMPRISING COPPER | BASF SE (DE) | 2024-07-24 | — | — | EP | claimed |
| CN-114042455-B | Carbonyl selective hydrogenation catalyst and preparation method and application thereof | 浙江新和成股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-116392986-B | Continuous production system for carbonylation of 1- (4-isobutylphenyl) ethanol and operation method | 北京思达流体科技有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-115353448-B | Synthesis method of ibuprofen, catalytic system and application of catalytic system | 浙江新和成股份有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-116392986-A | Continuous production system for carbonylation of 1- (4-isobutylphenyl) ethanol and operation method | 北京思达流体科技有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-115487866-A | Covalent organic framework material coupled nano metal catalyst and preparation method thereof | 浙江大学 | 2022-12-20 | — | — | CN | claimed |
| CN-115353448-A | Ibuprofen synthesis method, catalytic system and application thereof | 浙江新和成股份有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-114195633-A | Synthesis method of ibuprofen impurity F | 浙江新和成股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| US-20220041533-A1 | PROCESS FOR PRODUCING 1-(4-ISOBUTYLPHENYL)ETHANOL BY HYDROGENATION OF 1-(4-ISOBUTYL-PHENYL)ETHANONE IN THE PRESENCE OF A CATALYST COMPOSITION COMPRISING COPPER | BASF SE (DE) | 2022-02-10 | — | — | US | claimed |
| US-4988652-A | Process for recovering catalyst for use in preparing α-(4-isobutylphenyl)propionic acid | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1991-01-29 | — | — | US | claimed |
| US-4981995-A | CARBONYLATION CATALYST | HNA HOLDINGS, INC. | 1991-01-01 | — | — | US | claimed |
| EP-0400892-A2 | Method for producing ibuprofen | HOECHST CELANESE CORPORATION (US) | 1990-12-05 | — | — | EP | claimed |
| EP-0387502-A1 | Process for recovering catalyst for use in preparing 1-(4-isobutylphenyl) propionic acid | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-09-19 | — | — | EP | claimed |
| US-4937362-A | Process for production of α-(4-isobutylphenyl)propionic acid | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-06-26 | — | — | US | claimed |
| US-4929773-A | CATALYTIC HYDROGENATION OF ISOBUTYLACETOPHENONE | HOECHST CELANESE CORPORATION (US) | 1990-05-29 | — | — | US | claimed |
| EP-0361021-A1 | Process for production of alpha-(4-isobutylphenyl)propionic acid | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-04-04 | — | — | EP | claimed |
| EP-0358420-A2 | Method of producing 1-(4'-isobutylphenyl) ethanol | HOECHST CELANESE CORPORATION (US) | 1990-03-14 | — | — | EP | claimed |
| EP-0337803-A1 | Catalyst recycle in the carbonylation of isobutylphenylethanol to ibuprofen | HOECHST CELANESE CORPORATION (US) | 1989-10-18 | — | — | EP | claimed |
| EP-0326027-A1 | Process for the purification of 2-(4-isobutylphenyl)-propionic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041533-A1 | PROCESS FOR PRODUCING 1-(4-ISOBUTYLPHENYL)ETHANOL BY HYDROGENATION OF 1-(4-ISOBUTYL-PHENYL)ETHANONE IN THE PRESENCE OF A CATALYST COMPOSITION COMPRISING COPPER | ADH1C, AP1S1, ADH1A | PTGS1 800/4885PTGS2 1444/4885CXCR1 3313/4885 |
| US-12378174-B2 | Process for producing 1-(4-isobutylphenyl)ethanol by hydrogenation of 1-(4-isobutyl-phenyl)ethanone in the presence of a catalyst composition comprising copper | ADH1C, AP1S1, ADH1A | PTGS1 800/4885PTGS2 1444/4885CXCR1 3313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.