Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 15/20 | 0.77 |
| ▸ | F10 | P00742 | 2/20 | 0.61 |
| ▸ | CCR9 | P51686 | 1/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434124 | 0.88 | CCR2 (0.66) | CCR2F10PLA2G10GPR35 | |
| SCHEMBL27658570 | 0.83 | CCR2 (0.82) | CCR2CCR9ABCB11GPR35 | |
| SCHEMBL3191922 | 0.79 | CCR2 (0.76) | CCR2CCR9ABCB11GPR35 | |
| SCHEMBL2000903 | 0.77 | CCR2 (0.75) | CCR2F10CCR9ABCB11GPR35 | |
| SCHEMBL2643256 | 0.77 | CCR2 (0.64) | CCR2CCR9GPR35 | |
| SCHEMBL6436016 | 0.76 | CCR2 (1.00) | CCR2CCR9ABCB11GPR35 | |
| SCHEMBL3967526 | 0.76 | CCR2 (1.00) | CCR2CCR9ABCB11 | |
| SCHEMBL3198946 | 0.76 | CCR2 (0.71) | CCR2CCR9ABCB11 | |
| SCHEMBL6308068 | 0.76 | CCR2 (0.73) | CCR2CCR9ABCB11GPR35 | |
| SCHEMBL4537478 | 0.75 | CCR2 (0.81) | CCR2CCR9ABCB11GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |