Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.66 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.64 |
| ▸ | F10 | P00742 | 12/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436875 | 0.88 | CCR2 (0.77) | CCR2PLA2G10F10GPR35 | |
| SCHEMBL6432819 | 0.86 | F10 (0.84) | CCR2PLA2G10F10F2 | |
| SCHEMBL3963187 | 0.84 | PLA2G10 (0.83) | CCR2PLA2G10F10F2GPR35 | |
| SCHEMBL27497454 | 0.81 | PLA2G10 (0.74) | CCR2PLA2G10F10F2GPR35 | |
| SCHEMBL5378162 | 0.81 | CCR2 (1.00) | CCR2PLA2G10F10GPR35 | |
| SCHEMBL27811964 | 0.78 | CCR2 (0.76) | CCR2PLA2G10F10GPR35 | |
| SCHEMBL7076414 | 0.78 | CCR2 (0.76) | CCR2PLA2G10F10GPR35 | |
| SCHEMBL3957310 | 0.78 | CCR2 (1.00) | CCR2PLA2G10F10GPR35 | |
| SCHEMBL12589590 | 0.76 | F10 (1.00) | F10F2 | |
| SCHEMBL6433076 | 0.75 | CCR2 (0.77) | CCR2PLA2G10F10GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |