SCHEMBL6437174

SCHEMBL6437174

C=C(C)COCCC(=C)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.32
CES2 O00748 1/20 0.31
THRB P10828 1/20 0.31
TET3 O43151 1/20 0.30
TET1 Q8NFU7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10455920 0.88 CES2 (0.37) TET2CES2
SCHEMBL11300608 0.83 LMNA (0.39) CES2THRB
SCHEMBL9436946 0.82 TET2 (0.37) TET2TET3TET1
SCHEMBL10935297 0.82 TDP1 (0.37) CES2
SCHEMBL15136484 0.80 TET2 (0.35) TET2TET3TET1
SCHEMBL8355965 0.80 TET2 (0.36) TET2THRBTET3TET1
SCHEMBL11124813 0.80 TET2 (0.36) TET2THRBTET3TET1
SCHEMBL43126 0.78 THRB (0.45) TET2THRBTET3TET1
SCHEMBL4740516 0.77 BTN3A1 (0.39)
SCHEMBL5164196 0.77 TET2 (0.33) TET2THRBTET3TET1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6881858-B2 Asymmetric (meth)acrylate crosslinking agents ROEHM GMBH & CO. KG (DE) 2005-04-19 US disclosed
US-20020095016-A1 Asymmetric (meth)acrylate crosslinking agents ROEHM GMBH & CO.KG (DE) 2002-07-18 US disclosed
EP-0275452-A1 Process for the quasi-ionic polymerization of derivatives of acrylic acid BAYER AG (DE) 1988-07-27 EP disclosed
EP-0068887-B1 \"LIVING\" POLYMERS AND PROCESS FOR THEIR PREPARATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-09-24 EP disclosed
US-4417034-A POLYMERIZING ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANO-SILICON, -TIN, OR-GERMANIUM INITIATORS E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-22 US disclosed
EP-0068887-A1 \"Living\" polymers and process for their preparation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-05 EP disclosed