Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.62 |
| ▸ | CCKAR | P32238 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968115 | 0.85 | MEN1 (0.56) | CCKBRCCKARMEN1LMNAALB | |
| SCHEMBL4819173 | 0.85 | MEN1 (0.69) | CCKBRCCKARMEN1LMNAALB | |
| SCHEMBL642854 | 0.83 | CCKBR (0.55) | CCKBRCCKAR | |
| SCHEMBL641962 | 0.83 | MEN1 (0.66) | CCKBRCCKARMEN1LMNAALB | |
| SCHEMBL643974 | 0.82 | CHRM1 (0.65) | CCKBRCCKARMEN1LMNAALB | |
| Cyclohexane SCHEMBL3971471 | 0.82 | MEN1 (0.65) | CCKBRCCKARMEN1LMNAALB | |
| SCHEMBL643309 | 0.81 | CCKBR (0.62) | CCKBRCCKARMEN1LMNAALB | |
| SCHEMBL5418531 | 0.80 | LMNA (0.72) | CCKBRCCKARMEN1LMNAALB | |
| SCHEMBL642028 | 0.79 | CCKBR (0.62) | CCKBRCCKARMEN1LMNAALB | |
| SCHEMBL643084 | 0.79 | CCKBR (0.71) | CCKBRCCKARMEN1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119630-B2 | Benzodiazepine derivatives and pharmaceutical compositions containing them | ARROW THERAPEUTICS LIMITED (GB) | 2012-02-21 | — | — | US | disclosed |