Methacrylic Acid

Methacrylic Acid

SCHEMBL6437286

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.OCC(CO)C(CO)CO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.45
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 1/20 0.34
OR51E2 Q9H255 2/20 0.33
TET2 Q6N021 4/20 0.32
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
ALDH1A1 P00352 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL10565942 1.00 TGFBR1 (0.45) TGFBR1TDP1TSHROR51E2TET2
Methacrylic Acid SCHEMBL35272 0.89 TGFBR1 (0.38) TGFBR1
Methacrylic Acid SCHEMBL35548 0.89 TGFBR1 (0.38) TGFBR1
Methacrylic Acid SCHEMBL418671 0.85 TGFBR1 (0.39) TGFBR1TDP1TSHROR51E2TET2
Methacrylic Acid SCHEMBL11573882 0.85 TGFBR1 (0.39) TGFBR1TDP1TSHR
Methacrylic Acid SCHEMBL10783061 0.85 TGFBR1 (0.36) TGFBR1
Methacrylic Acid SCHEMBL3151099 0.83 TGFBR1 (0.45) TGFBR1TDP1TSHROR51E2TET2
Methacrylic Acid SCHEMBL9815885 0.83 TGFBR1 (0.45) TGFBR1TDP1TSHROR51E2TET2
Methacrylic Acid SCHEMBL5683702 0.83 TSHR (0.50) TGFBR1TDP1TSHROR51E2TET2
Methacrylic Acid SCHEMBL5595699 0.83 TGFBR1 (0.45) TGFBR1TDP1TSHROR51E2TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4526920-A Contains poly(meth)acrylic ester of oxy or polyoxyalkane polyol, polymerization initiator, filler MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-02 US claimed
CN-109964152-B Formable antiglare polymer film 科思创德国股份有限公司 2021-12-28 CN disclosed
EP-1326901-B1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS CIBA SC HOLDING AG (CH) 2005-06-08 EP disclosed
US-20030164580-A1 Acylphosphine oxide photoinitiators in methacrylate casting resins CIBA SPECIALTY CHEMICALS CORP. 2003-09-04 US disclosed
EP-1326901-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS Ciba SC Holding AG (CH) 2003-07-16 EP disclosed
WO-2002022697-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-03-21 WO disclosed
EP-0100688-B1 CURABLE COATING COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-04-22 EP disclosed
US-4526920-A Contains poly(meth)acrylic ester of oxy or polyoxyalkane polyol, polymerization initiator, filler MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-02 US disclosed
EP-0100688-A2 Curable coating composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-02-15 EP disclosed