SCHEMBL6437397

SCHEMBL6437397

Oc1c(Cl)c(O)c(Cl)c(Cl)c1Cl

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 0.91
TSHR P16473 7/20 0.91
HPGD P15428 7/20 0.91
ALDH1A1 P00352 3/20 0.91
MEN1 O00255 2/20 0.91
LMNA P02545 2/20 0.91
MAPT P10636 2/20 0.91
KMT2A Q03164 2/20 0.91
CYP1A2 P05177 4/20 0.50
CYP2C9 P11712 4/20 0.50
HIF1A Q16665 3/20 0.50
CASP1 P29466 1/20 0.47
CYP2C19 P33261 1/20 0.43
MAPK1 P28482 3/20 0.42
CYP3A4 P08684 5/20 0.40
USP2 O75604 1/20 0.40
TP53 P04637 1/20 0.40
GLA P06280 1/20 0.40
THRB P10828 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentachlorophenol SCHEMBL5315995 0.95 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL23121452 0.95 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL1492 0.95 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL1330735 0.95 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL41162 0.91 HSD17B10 (0.91) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL21177789 0.91 HSD17B10 (0.91) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL22027593 0.91 HSD17B10 (0.91) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL21647360 0.91 HSD17B10 (0.91) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL3751225 0.91 HSD17B10 (0.91) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL5167937 0.91 HSD17B10 (0.91) HSD17B10TSHRHPGDALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2636665-B1 METHOD FOR PRODUCING ESTER UNIV NAGOYA NAT UNIV CORP (JP) 2016-06-22 EP disclosed
US-8853426-B2 Method for manufacturing ester NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-10-07 US disclosed
EP-2636665-A1 METHOD FOR PRODUCING ESTER National University Corporation Nagoya University (JP) 2013-09-11 EP disclosed
US-20130217898-A1 METHOD FOR MANUFACTURING ESTER NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2013-08-22 US disclosed
EP-1009729-B1 HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM MINNESOTA MINING & MFG (US) 2005-01-19 EP disclosed
CN-1125030-C Halogenated acrylates and polymers made therefrom MINNESOTA MINING & MFG (US) 2003-10-22 CN disclosed
US-6362379-B2 ACRYLATES HAVING HIGH DEGREE OF HALOGENATION AND POLYMERS USING THESE MONOMERS; USEFUL FOR OPTICAL WAVEGUIDES AND TELECOMMUNICATION 3M INNOVATIVE PROPERTIES COMPANY 2002-03-26 US disclosed
US-6313245-B1 USED IN OPTICAL DEVICES INCLUDING OPTICAL WAVEGUIDES AND INTERCONNECTING DEVICES 3M INNOVATIVE PROPERTIES COMPANY 2001-11-06 US disclosed
US-20010037028-A1 Halogenated acrylates and polymers derived therefrom 3M INNOVATIVE PROPERTIES COMPANY 2001-11-01 US disclosed
US-6288266-B1 HALOGENATED ACRYLATES OR THIOACRYLATES FOR POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2001-09-11 US disclosed
EP-0292629-A2 Polycondensation catalyst SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-11-30 EP disclosed
US-4778873-A MIXTURE OF PHOSPHORUS-SILICON COMPOUND AND ACID ACCEPTOR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-10-18 US disclosed
EP-0277907-A2 Low temperature synthesis of condensation polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-08-10 EP disclosed
US-4668762-A OXYGEN-SILICON-PHOSPHORUS-CONTAINING COMPOUNDS, ACID ACCEPTORS AND HALO COMPOUND TO MAKE POLYESTERS,-UREAS AND AMIDES AT LOW TEMPERATURE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-05-26 US disclosed
US-4361623-A REACTION PRODUCT OF NITROGEN COMPOUND AND HALOGENATED DIOL BASF WYANDOTTE CORPORATION (US) 1982-11-30 US disclosed
US-4312966-A DISPERSION IN POLYMERIC FIBER OF HALOGENATED POLYESTER OF POLYOXYALKYLENE COMPOUND HAVING AMINE NUCLEUS BASF WYANDOTTE CORPORATION (US) 1982-01-26 US disclosed
US-4304801-A REACTION PRODUCT OF AMINE-INITIATED ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER, HALOGENATED DIACID, AND DIOL BASF WYANDOTTE CORPORATION (US) 1981-12-08 US disclosed
US-4303767-A Flame retardant antistatic additives and antistatic fibers BASF WYANDOTTE CORPORATION (US) 1981-12-01 US disclosed
US-4294944-A POLYOXYALKYLENE-AMINES BASF WYANDOTTE CORPORATION (US) 1981-10-13 US disclosed
US-4229554-A HALOGENATED POLYETHER-POLYESTER COPOLYMERS BASF WYANDOTTE CORPORATION (US) 1980-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010037028-A1 Halogenated acrylates and polymers derived therefrom ZYX, ACR, ORMDL3 HSD17B10 2750/4885TSHR 1965/4885HPGD 3553/4885
US-20130217898-A1 METHOD FOR MANUFACTURING ESTER CBR3, BCKDK, ACSL4 HSD17B10 61/4885TSHR 3780/4885HPGD 1174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.