SCHEMBL6437683

SCHEMBL6437683

CCCCC1OC1CCO

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 3/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PRKCA P17252 1/20 0.35
SPHK2 Q9NRA0 3/20 0.33
SPHK1 Q9NYA1 3/20 0.33
GBA1 P04062 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6434474 0.93 SMN1; SMN2 (0.43) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL6432754 0.91 LMNA (0.46) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL6436160 0.91 LMNA (0.46) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL6437114 0.91 LMNA (0.46) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL6440601 0.88 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL7110791 0.87 TSHR (0.38) ALDH1A1LMNATSHRSPHK2SPHK1
SCHEMBL51186 0.87 TSHR (0.38) ALDH1A1LMNATSHRSPHK2SPHK1
SCHEMBL9133300 0.87 TSHR (0.38) ALDH1A1LMNATSHRSPHK2SPHK1
SCHEMBL11443981 0.86 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL6433662 0.86 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102482467-A Thermoplastic resin composition YOKOHAMA RUBBER CORP 2012-05-30 CN disclosed
CN-102361939-A Thermoplastic resin composition YOKOHAMA RUBBER CO LTD 2012-02-22 CN disclosed
EP-1172400-B1 THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY YUPO CORP (JP) 2005-12-28 EP disclosed
US-6586106-B2 Ink transfer, adhesion and aging stability, and being satisfactory in back ghost when offset printing using oxidation polymerization type ink is performed on both faces YUPO CORPORATION (JP) 2003-07-01 US disclosed
US-20020054991-A1 Thermoplastic resin film satisfactory in printability YUPO CORPORATION (JP) 2002-05-09 US disclosed
EP-1172400-A1 THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY Yupo Corporation (JP) 2002-01-16 EP disclosed