Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567585 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ACES1CYP1A2CYP2C19 | |
| SCHEMBL27639696 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2HIF1ACES1CYP1A2CYP2C19 | |
| SCHEMBL5940486 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL1272430 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2HIF1ACES1CYP1A2CYP2C19 | |
| SCHEMBL2032323 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2HIF1ACES1CYP1A2CYP2C19 | |
| SCHEMBL1272429 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2HIF1ACES1CYP1A2CYP2C19 | |
| SCHEMBL8153532 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1ACES1CYP1A2CYP2C19 | |
| SCHEMBL5235928 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1ACES1CYP1A2CYP2C19 | |
| Methane SCHEMBL28715292 | 0.74 | SMN1; SMN2 (0.62) | SMN1; SMN2HIF1ACES1CYP1A2CYP2C19 | |
| SCHEMBL22190022 | 0.74 | SMN1; SMN2 (0.62) | SMN1; SMN2HIF1ACES1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030735-A1 | TRIAZINES DERIVATIVES AS CELL ADHESION INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2005-04-07 | — | — | WO | claimed |
| US-20150045328-A1 | DISUBSTITUTED ARYL OXY DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS | ALLERGAN, INC. | 2015-02-12 | — | — | US | disclosed |
| US-20050256160-A1 | Beta-alanine derivatives and the use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045328-A1 | DISUBSTITUTED ARYL OXY DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS | S1PR1, S1PR3, S1PR2 | SMN1; SMN2 3562/4885HIF1A 2285/4885CES1 1100/4885 |
| US-20050256160-A1 | Beta-alanine derivatives and the use thereof | TGFB1, PML, APOB | SMN1; SMN2 57/4885HIF1A 518/4885CES1 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.