Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455861 | 1.00 | ALDH1A1 (0.46) | ALDH1A1ALOX12NPSR1HCRTR1CYP1A2 | |
| SCHEMBL4330730 | 0.93 | ALDH1A1 (0.46) | ALDH1A1ALOX12NPSR1HCRTR1CYP1A2 | |
| SCHEMBL4330727 | 0.93 | ALDH1A1 (0.46) | ALDH1A1ALOX12NPSR1HCRTR1CYP1A2 | |
| SCHEMBL4329336 | 0.86 | ALDH1A1 (0.49) | ALDH1A1ALOX12NPSR1HCRTR1CYP1A2 | |
| SCHEMBL4329338 | 0.86 | ALDH1A1 (0.49) | ALDH1A1ALOX12NPSR1HCRTR1CYP1A2 | |
| SCHEMBL4334397 | 0.83 | CA1 (0.53) | ALDH1A1ALOX12NPSR1HCRTR1CYP1A2 | |
| SCHEMBL4334400 | 0.83 | CA1 (0.53) | ALDH1A1ALOX12NPSR1HCRTR1CYP1A2 | |
| SCHEMBL4338895 | 0.82 | PKM (0.44) | ALDH1A1ALOX12NPSR1HCRTR1CYP1A2 | |
| SCHEMBL4338897 | 0.82 | PKM (0.44) | ALDH1A1ALOX12NPSR1HCRTR1CYP1A2 | |
| SCHEMBL4329352 | 0.82 | MAPK1 (0.44) | ALDH1A1KDM4EMAPK1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050069555-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050069555-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | MAVS, IRF3, HAVCR2 | ALDH1A1 1173/4885ALOX12 952/4885NPSR1 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.