Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438225 | 0.88 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL6439571 | 0.83 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL8637748 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL5674799 | 0.78 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL8796825 | 0.77 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL7780834 | 0.77 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL3866592 | 0.77 | CA2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL6441773 | 0.76 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL6440845 | 0.76 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL6438268 | 0.75 | PTGS2 (0.52) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534683-A4 | CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2005-08-24 | — | — | EP | disclosed |
| EP-1534683-A2 | CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | Nitromed, Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004002409-A2 | CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2004-01-08 | — | — | WO | disclosed |