Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA8 | P11142 | 4/20 | 0.52 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | ADK | P55263 | 2/20 | 0.48 |
| ▸ | GAPDH | P04406 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26487688 | 0.90 | ADORA2A (0.53) | HSPA8HSPA5RXFP1ADKGAPDH | |
| SCHEMBL14075808 | 0.88 | HSPA8 (0.57) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL18740403 | 0.88 | HSPA8 (0.57) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL6439878 | 0.86 | NADK (0.54) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL27626941 | 0.86 | NADK (0.54) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL28646728 | 0.86 | LMNA (0.61) | HSPA8HSPA5RXFP1ADKGAPDH | |
| 8-Chloroadenosine SCHEMBL31064773 | 0.81 | HSPA8 (0.78) | HSPA8HSPA5RXFP1ADKGAPDH | |
| 8-Chloroadenosine SCHEMBL987728 | 0.81 | HSPA8 (0.78) | HSPA8HSPA5RXFP1ADKGAPDH | |
| 8-Chloroadenosine SCHEMBL19680324 | 0.81 | HSPA8 (0.78) | HSPA8HSPA5RXFP1ADKGAPDH | |
| 8-Chloroadenosine SCHEMBL987731 | 0.81 | HSPA8 (0.78) | HSPA8HSPA5RXFP1ADKGAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511757-A1 | NEW COMPOUNDS FOR MODULATING THE ACTIVITY OF EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP (EPACS) | Kylix B.V. (NL) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003104250-A1 | NEW COMPOUNDS FOR MODULATING THE ACTIVITY OF EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP (EPACS) | KYLIX, B. V. (NL) | 2003-12-18 | — | — | WO | disclosed |