Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439350 | 1.00 | CA2 (0.35) | CA2PRKG1 | |
| SCHEMBL9063602 | 0.84 | AOC3 (0.43) | — | |
| SCHEMBL15229070 | 0.82 | SLC6A2 (0.38) | — | |
| SCHEMBL16554196 | 0.78 | SLC6A4 (0.38) | — | |
| SCHEMBL15229246 | 0.78 | SLC6A4 (0.38) | — | |
| SCHEMBL1739510 | 0.78 | GSR (0.44) | CA2 | |
| SCHEMBL14984000 | 0.78 | GSR (0.44) | CA2 | |
| SCHEMBL8405099 | 0.78 | GSR (0.44) | CA2 | |
| SCHEMBL31201875 | 0.77 | CA2 (0.33) | CA2 | |
| SCHEMBL5223462 | 0.75 | AOC3 (0.37) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087943-B1 | THERAPEUTIC BIARYL DERIVATIVES | GLAXO GROUP LTD (GB) | 2005-08-17 | — | — | EP | disclosed |
| US-6251925-B1 | AN AGONISTS FOR HUMAN BETA-3 ADRENOCEPTOR | GLAXO WELLCOME INC. | 2001-06-26 | — | — | US | disclosed |
| EP-1087943-A1 | THERAPEUTIC BIARYL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065877-A1 | THERAPEUTIC BIARYL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-12-23 | — | — | WO | disclosed |