SCHEMBL6439382

SCHEMBL6439382

[CH2]C(C(C)CCCC(C)C)C(C(=O)O)N1CC(=O)NC(Cc2ccccc2)C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 3/20 0.41
HDAC1 Q13547 3/20 0.41
HDAC8 Q9BY41 2/20 0.41
HDAC4 P56524 2/20 0.37
PLA2G10 O15496 2/20 0.35
PLA2G5 P39877 2/20 0.35
SSTR1 P30872 2/20 0.35
SSTR2 P30874 2/20 0.35
SSTR4 P31391 2/20 0.35
SSTR3 P32745 2/20 0.35
SSTR5 P35346 2/20 0.35
SOAT2 O75908 1/20 0.35
SOAT1 P35610 1/20 0.35
TRPM8 Q7Z2W7 1/20 0.35
PLAU P00749 1/20 0.35
PLAUR Q03405 1/20 0.35
OPRK1 P41145 2/20 0.34
ALOX15 P16050 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC2 Q92769 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8557209 0.69 HDAC6 (0.44) HDAC6HDAC1HDAC8HDAC4PLA2G10
SCHEMBL9437480 0.67 MME (0.42) HDAC6HDAC1HDAC8SOAT2
Acetic Acid SCHEMBL9020771 0.67 PLA2G10 (0.54) HDAC6HDAC1HDAC8PLA2G10PLA2G5
SCHEMBL13074467 0.66 GHSR (0.57) HDAC6HDAC1HDAC8PLA2G10PLA2G5
SCHEMBL2543245 0.66 GHSR (0.57) HDAC6HDAC1HDAC8PLA2G10PLA2G5
SCHEMBL27469829 0.66 GHSR (0.57) HDAC6HDAC1HDAC8PLA2G10PLA2G5
SCHEMBL3956087 0.65 HDAC6 (0.62) HDAC6HDAC1HDAC8PLA2G10PLA2G5
SCHEMBL9020761 0.63 HDAC6 (0.59) HDAC6HDAC1HDAC8PLA2G10PLA2G5
SCHEMBL877776 0.63 HDAC6 (0.73) HDAC6HDAC1HDAC8HDAC4PLA2G10
SCHEMBL876552 0.63 HDAC6 (0.73) HDAC6HDAC1HDAC8HDAC4PLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050077648-A1 Solution casting method and polymer film FUJIFILM CORPORATION (JP) 2005-04-14 US disclosed