Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9020771 | 0.73 | PLA2G10 (0.54) | HDAC6HDAC1HDAC8GAAPOLB | |
| SCHEMBL13074467 | 0.70 | GHSR (0.57) | HDAC6HDAC1HDAC8GAAPOLB | |
| SCHEMBL2543245 | 0.70 | GHSR (0.57) | HDAC6HDAC1HDAC8GAAPOLB | |
| SCHEMBL27469829 | 0.70 | GHSR (0.57) | HDAC6HDAC1HDAC8GAAPOLB | |
| SCHEMBL6439382 | 0.69 | HDAC6 (0.41) | HDAC6HDAC1HDAC8SSTR1SSTR2 | |
| SCHEMBL3956087 | 0.68 | HDAC6 (0.62) | HDAC6HDAC1HDAC8GAAPOLB | |
| SCHEMBL9437480 | 0.67 | MME (0.42) | HDAC6HDAC1HDAC8 | |
| SCHEMBL9020761 | 0.66 | HDAC6 (0.59) | HDAC6HDAC1HDAC8PLA2G10PLA2G5 | |
| SCHEMBL876552 | 0.66 | HDAC6 (0.73) | HDAC6HDAC1HDAC8GAAPOLB | |
| SCHEMBL877776 | 0.66 | HDAC6 (0.73) | HDAC6HDAC1HDAC8GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773441-A | PRODRUGS; ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1998-06-30 | — | — | US | disclosed |