Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | SDCBP | O00560 | 2/20 | 0.41 |
| ▸ | SDC2 | P34741 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.40 |
| ▸ | ITGAL | P20701 | 4/20 | 0.40 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437576 | 0.77 | LMNA (0.52) | HDAC6HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL873588 | 0.74 | HDAC6 (0.62) | HDAC6HDAC1HDAC8KMT2A | |
| SCHEMBL873589 | 0.74 | HDAC6 (0.62) | HDAC6HDAC1HDAC8KMT2A | |
| SCHEMBL6439382 | 0.67 | HDAC6 (0.41) | HDAC6HDAC1HDAC8SOAT2 | |
| SCHEMBL8557209 | 0.67 | HDAC6 (0.44) | HDAC6HDAC1HDAC8 | |
| SCHEMBL13879474 | 0.67 | MAPT (0.57) | — | |
| SCHEMBL13879408 | 0.66 | HDAC6 (0.59) | HDAC6HDAC1MEN1KMT2A | |
| SCHEMBL5557284 | 0.65 | HDAC6 (0.45) | HDAC6HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL5557293 | 0.65 | HDAC6 (0.45) | HDAC6HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL7448764 | 0.65 | CXCR4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340802-A | Central nervous system disorders | ABBOTT LABORATORIES (US) | 1994-08-23 | — | — | US | disclosed |