SCHEMBL6440113

SCHEMBL6440113

Cc1csc(C(O)(c2ccc(CCC34OCC(C)(CO3)CO4)cc2)c2cc(C)cs2)c1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6437534 0.82 ESR1 (0.32) ESR1
SCHEMBL6440105 0.75 EPHX2 (0.33)
SCHEMBL6437151 0.75 SMN1; SMN2 (0.39)
SCHEMBL6437750 0.72 FFAR1 (0.45) ESR1
SCHEMBL6436895 0.67 TAAR1 (0.39)
SCHEMBL6441205 0.64 CYP4F2 (0.40) ESR1
SCHEMBL13939419 0.63
SCHEMBL6469982 0.59 L3MBTL1 (0.47) ESR1
SCHEMBL13939397 0.57 HRH3 (0.33)
SCHEMBL13535442 0.57 HMOX1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1506959-A2 Derivatised molecules for mass spectrometry OXFORD GENE TECHNOLOGY IP LIMITED (GB) 2005-02-16 EP disclosed