Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.44 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438258 | 0.89 | HTR6 (0.42) | HTR6AVPR1BOXTRSMN1; SMN2USP2 | |
| SCHEMBL3565168 | 0.85 | HTR6 (0.52) | HTR6AVPR1BOXTRPKMALDH1A1 | |
| SCHEMBL6442221 | 0.79 | AVPR1B (0.37) | HTR6AVPR1BSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL3555819 | 0.77 | HTR6 (0.54) | HTR6AVPR1BOXTRSMN1; SMN2USP2 | |
| SCHEMBL3556128 | 0.75 | HTR6 (0.50) | HTR6 | |
| SCHEMBL3553338 | 0.74 | HTR6 (0.45) | HTR6PKMALDH1A1 | |
| SCHEMBL6435967 | 0.74 | HTR6 (0.54) | HTR6PTGDR2 | |
| SCHEMBL6440415 | 0.74 | PSEN1 (0.48) | HTR6ALDH1A1GAATSHRPTGDR2 | |
| SCHEMBL6526507 | 0.74 | LMNA (0.47) | HTR6PKMSMN1; SMN2GAARECQL | |
| SCHEMBL3558220 | 0.73 | HTR6 (0.43) | HTR6AVPR1BOXTRSMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | claimed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |