Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.54 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526507 | 0.88 | LMNA (0.47) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6440415 | 0.88 | PSEN1 (0.48) | HTR6ALDH3A1PTGDR2PTGDRNOD1 | |
| SCHEMBL6524962 | 0.86 | NOD1 (0.46) | HTR6NOD1PSEN1PSEN2APH1B | |
| SCHEMBL3563139 | 0.84 | HTR6 (0.56) | HTR6ALDH3A1PTGDR2PTGDRNOD1 | |
| SCHEMBL6444246 | 0.84 | PTGDR2 (0.48) | HTR6PTGDR2PTGDRNOD1NOD2 | |
| SCHEMBL6440894 | 0.84 | PTGDR2 (0.47) | HTR6PTGDR2PTGDRNOD1NOD2 | |
| SCHEMBL6440512 | 0.76 | PTGDR2 (0.48) | HTR6ALDH3A1PTGDR2PTGDRNOD1 | |
| SCHEMBL6439680 | 0.76 | HTR6 (0.41) | HTR6PTGDR2PTGDR | |
| SCHEMBL6442219 | 0.76 | PTGDR2 (0.43) | HTR6ALDH3A1PTGDR2PTGDRNOD1 | |
| SCHEMBL6442221 | 0.74 | AVPR1B (0.37) | HTR6PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | claimed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |