Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6021991 | 1.00 | ITGB3 (0.55) | ITGB3ITGA2BALDH1A1ALOX15TACR1 | |
| SCHEMBL6441561 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL148500 | 0.80 | LMNA (0.44) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL6443111 | 0.78 | SLC7A5 (0.50) | ITGB3ITGA2B | |
| SCHEMBL220648 | 0.76 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15TACR1 | |
| SCHEMBL7372270 | 0.76 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15TACR1 | |
| SCHEMBL479010 | 0.76 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15TACR1 | |
| SCHEMBL219151 | 0.76 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15TACR1 | |
| SCHEMBL26661077 | 0.76 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15TACR1 | |
| SCHEMBL3927621 | 0.76 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1ALOX15TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1574516-A1 | Antithrombotic compound | Sanofi-Aventis (FR) | 2005-09-14 | — | — | EP | disclosed |