Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 4/20 | 0.66 |
| ▸ | BACE1 | P56817 | 4/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.62 |
| ▸ | STAT3 | P40763 | 3/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.62 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440492 | 1.00 | JUN (0.70) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL7051812 | 0.90 | JUN (0.59) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL6441910 | 0.86 | BACE1 (0.62) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL6440618 | 0.86 | BACE1 (0.62) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL242412 | 0.85 | GSK3B (0.87) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL6727006 | 0.85 | GSK3B (0.87) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL3680675 | 0.85 | GSK3B (0.87) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL3433171 | 0.85 | GSK3B (0.87) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL29855588 | 0.85 | GSK3B (0.87) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL608770 | 0.85 | BACE1 (0.70) | JUNCYP1A2CYP2D6GSK3BBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900356-B2 | Polyhydroxy curcumins having antioxidant activity | LAILA IMPEX (IN) | 2005-05-31 | — | — | US | claimed |
| US-6900356-B2 | Polyhydroxy curcumins having antioxidant activity | LAILA IMPEX (IN) | 2005-05-31 | — | — | US | disclosed |