Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 3/20 | 0.55 |
| ▸ | BACE1 | P56817 | 3/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.55 |
| ▸ | STAT3 | P40763 | 3/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440492 | 0.90 | JUN (0.70) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL6440499 | 0.90 | JUN (0.70) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL3335463 | 0.81 | CYP1A2 (0.81) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL3335467 | 0.81 | CYP1A2 (0.81) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL197850 | 0.79 | PKM (0.87) | CYP1A2CYP2D6CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL10085810 | 0.79 | PKM (0.87) | CYP1A2CYP2D6CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL29537849 | 0.79 | PKM (0.87) | CYP1A2CYP2D6CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL561928 | 0.76 | CYP2D6 (0.67) | CYP1A2CYP2D6CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL608770 | 0.76 | BACE1 (0.70) | JUNCYP1A2CYP2D6GSK3BBACE1 | |
| SCHEMBL3433171 | 0.76 | GSK3B (0.87) | JUNCYP1A2CYP2D6CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216600-A1 | Novel polyhydroxy curcumins having antioxidant activity | LAILA IMPEX (IN) | 2003-11-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216600-A1 | Novel polyhydroxy curcumins having antioxidant activity | DBH, KEAP1, HMOX1 | JUN 966/4885CYP1A2 725/4885CYP2D6 1068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.