Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.62 |
| ▸ | GSK3B | P49841 | 6/20 | 0.62 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.62 |
| ▸ | JUN | P05412 | 3/20 | 0.56 |
| ▸ | FOS | P01100 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440618 | 1.00 | BACE1 (0.62) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL6440499 | 0.86 | JUN (0.70) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL6440492 | 0.86 | JUN (0.70) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL16093483 | 0.84 | BACE1 (0.68) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL514059 | 0.78 | KDM4E (0.64) | BACE1CYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL514058 | 0.78 | KDM4E (0.64) | BACE1CYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL7565045 | 0.77 | BACE1 (0.40) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL16093484 | 0.77 | APP (0.58) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL609968 | 0.77 | GSK3B (1.00) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL609967 | 0.77 | GSK3B (1.00) | BACE1GSK3BTLR9JUNFOS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900356-B2 | Polyhydroxy curcumins having antioxidant activity | LAILA IMPEX (IN) | 2005-05-31 | — | — | US | claimed |
| US-20030216600-A1 | Novel polyhydroxy curcumins having antioxidant activity | LAILA IMPEX (IN) | 2003-11-20 | — | — | US | claimed |
| WO-2002083614-A1 | NOVEL POLYHYDROXY CURCUMINS HAVING ANTIOXIDANT ACTIVITY | LAILA, IMPEX (IN) | 2002-10-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216600-A1 | Novel polyhydroxy curcumins having antioxidant activity | DBH, KEAP1, HMOX1 | BACE1 1873/4885GSK3B 3364/4885TLR9 3151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.