⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1232005 | 0.95 | THRB (0.33) | — | |
| SCHEMBL11043033 | 0.86 | THRB (0.36) | — | |
| SCHEMBL65415 | 0.83 | THRB (0.36) | — | |
| SCHEMBL10608315 | 0.83 | THRB (0.42) | — | |
| SCHEMBL10791124 | 0.82 | ALOX15 (0.34) | — | |
| SCHEMBL10409153 | 0.82 | THRB (0.32) | — | |
| SCHEMBL1231375 | 0.79 | — | — | |
| SCHEMBL11177282 | 0.78 | HTT (0.33) | — | |
| SCHEMBL2452962 | 0.75 | THRB (0.40) | — | |
| SCHEMBL11171137 | 0.75 | THRB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474719-A4 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS LLC (US) | 2005-12-14 | — | — | EP | claimed |
| US-20050090612-A1 | Polymerization process and materials for biomedical applications | ZMS, L.L.C.; A CALIFORNIA LIMITED LIABILITY CORPORATION | 2005-04-28 | — | — | US | claimed |
| EP-1474719-A1 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS, LLC (US) | 2004-11-10 | — | — | EP | claimed |
| WO-2003071339-A1 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS, LLC (US) | 2003-08-28 | — | — | WO | claimed |
| CN-100349935-C | Polymerization methods and materials for biomedical applications | ZMS LLC (US) | 2007-11-21 | — | — | CN | disclosed |
| EP-1474719-A4 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS LLC (US) | 2005-12-14 | — | — | EP | disclosed |
| CN-1643435-A | Polymerization process and materials for biomedical applications | ZMS LLC (US) | 2005-07-20 | — | — | CN | disclosed |
| US-20050090612-A1 | Polymerization process and materials for biomedical applications | ZMS, L.L.C.; A CALIFORNIA LIMITED LIABILITY CORPORATION | 2005-04-28 | — | — | US | disclosed |
| EP-1474719-A1 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS, LLC (US) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003071339-A1 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS, LLC (US) | 2003-08-28 | — | — | WO | disclosed |
| US-4931523-A | HIGH DYEABILITY, REFRACTIVE INDEX | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4812032-A | DIBROMOSTYRENE, DIVINYLBENZENE, HALOGEN CONTAINING ACRYLATE OR METHACRYLATE | TORAY INDUSTRIES, INC. (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4721377-A | COPOLYMER OF DIBROMOSTYRENE, DI-(OR TRI-) (METH-)ACRYLATE AND MONO (METH-)ACRYLATE | TORAY INDUSTRIES, INC. (JP) | 1988-01-26 | — | — | US | disclosed |
| EP-0134861-B1 | RESIN MATERIAL FOR PLASTIC LENS AND LENS COMPOSED THEREOF | TORAY INDUSTRIES, INC. (JP) | 1987-12-09 | — | — | EP | disclosed |
| EP-0176874-A2 | A highly-refractive plastic lens | TORAY INDUSTRIES, INC. (JP) | 1986-04-09 | — | — | EP | disclosed |
| EP-0134861-A1 | Resin material for plastic lens and lens composed thereof | TORAY INDUSTRIES, INC. (JP) | 1985-03-27 | — | — | EP | disclosed |
| US-4487904-A | Urethanized acrylic resin material for plastic lens and lens composed thereof | TORAY INDUSTRIES, INC. (JP) | 1984-12-11 | — | — | US | disclosed |