Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313355 | 0.88 | GAA (0.57) | GAACDK1TP53GLAMAPT | |
| SCHEMBL8463975 | 0.86 | GAA (0.47) | GAACDK1FBP1TP53GLA | |
| SCHEMBL28433647 | 0.83 | GAA (0.45) | GAACDK1MAPTKMT2AALDH1A1 | |
| SCHEMBL10984018 | 0.82 | GAA (0.60) | GAACDK1TP53GLAMAPT | |
| SCHEMBL4047516 | 0.82 | GAA (0.45) | GAAKMT2AACLYALOX15ALDH1A1 | |
| SCHEMBL11072814 | 0.80 | KMT2A (0.40) | GAAKMT2AACLYALOX15ALDH1A1 | |
| SCHEMBL3633898 | 0.80 | GAA (0.47) | GAACDK1TP53GLAMAPT | |
| SCHEMBL694106 | 0.77 | GAA (0.41) | GAACDK1TP53MAPTKMT2A | |
| SCHEMBL3500652 | 0.77 | GAA (0.48) | GAACDK1MAPTKMT2AMEN1 | |
| SCHEMBL7932024 | 0.77 | GAA (0.53) | GAACDK1TP53GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1536685-A1 | PROCESS FOR PREPARING PASTE-EXTRUDED SULFONAMIDE COMPOSITIONS | E.I. du Pont de Nemours and Company (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004023876-A1 | PROCESS FOR PREPARING PASTE-EXTRUDED SULFONAMIDE COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-03-25 | — | — | WO | disclosed |