SCHEMBL4047516

SCHEMBL4047516

Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2c(C)cccc2C(=O)O)n1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
LMNA P02545 1/20 0.44
ALOX15 P16050 1/20 0.43
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
CYP2C9 P11712 1/20 0.41
TSHR P16473 2/20 0.41
PCTP Q9UKL6 2/20 0.41
STARD10 Q9Y365 1/20 0.41
ALDH1A1 P00352 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ACLY P53396 1/20 0.40
CAMK2D Q13557 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9322044 0.88 PCTP (0.48) GAALMNAALOX15KMT2APCTP
SCHEMBL11072814 0.88 KMT2A (0.40) GAALMNAALOX15KMT2AMEN1
SCHEMBL6313355 0.87 GAA (0.57) GAAKMT2ATSHR
SCHEMBL11069338 0.84 KMT2A (0.38) GAAALOX15KMT2AMEN1ALDH1A1
SCHEMBL8463975 0.82 GAA (0.47) GAAKMT2AACLY
SCHEMBL6440652 0.82 GAA (0.47) GAAALOX15KMT2AMEN1ALDH1A1
Sulfometuron SCHEMBL66180 0.82 LMNA (0.49) GAALMNAALOX15TSHRALDH1A1
Sulfometuron SCHEMBL29367129 0.82 LMNA (0.49) GAALMNAALOX15TSHRALDH1A1
SCHEMBL694106 0.82 GAA (0.41) GAAKMT2AALDH1A1KDM4E
SCHEMBL10987885 0.82 GAA (0.48) GAATSHRPCTPSTARD10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0575489-B1 WATER-DISPERSIBLE GRANULAR AGRICULTURAL COMPOSITIONS MADE BY HEAT EXTRUSION DU PONT (US) 1997-07-02 EP claimed
EP-0637909-B1 REVERSIBLE AGRICULTURAL GEL AND PASTE FORMULATIONS DU PONT (US) 1997-02-26 EP claimed
EP-0471284-B1 Herbicidal compositions IDEMITSU KOSAN CO (JP) 1995-01-18 EP claimed
EP-0375875-A2 A method to improve the protection of crops from herbicidal injury AMERICAN CYANAMID COMPANY (US) 1990-07-04 EP claimed
US-7622641-B2 Methods and compositions for providing tolerance to multiple herbicides PIONEER HI-BRED INT'L., INC. (US) 2009-11-24 US disclosed
US-20070079393-A1 Methods and compositions for providing tolerance to multiple herbicides PIONEER HI-BRED INTERNATIONAL, INC. (US) 2007-04-05 US disclosed
EP-0683157-B1 Sulfonylaminocarbonyltriazolinones as herbicides BAYER CROPSCIENCE AG (DE) 2004-05-26 EP disclosed
US-6291400-B1 Herbicidal compounds ZENECA LIMITED (GB) 2001-09-18 US disclosed
US-6150301-A Chemical abscission of fruits at low application rates WILCOX MERRILL (US) 2000-11-21 US disclosed
US-5958839-A HERBICIDALLY ACTIVE SUBSTITUTED CYCLIC DIONES ZENECA LITMITED (GB) 1999-09-28 US disclosed
EP-0283261-B2 Herbicidal substituted cyclic diones ZENECA LTD (GB) 1998-09-09 EP disclosed
US-5744610-A Herbicidal compounds ZENECA LIMITED (GB) 1998-04-28 US disclosed
WO-1990002486-A1 WATER-SOLUBLE OR WATER-DISPERSIBLE PESTICIDE GRANULES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-22 WO disclosed
EP-0355049-A2 Heterocyclic compounds ZENECA LIMITED (GB) 1990-02-21 EP disclosed
EP-0351021-A2 Herbicide mixtures SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-01-17 EP disclosed
EP-0303153-A2 1-Aryl pyrazoles BAYER AG (DE) 1989-02-15 EP disclosed
EP-0297427-A2 1-Arylpyrazole BAYER AG (DE) 1989-01-04 EP disclosed
EP-0283261-A2 Herbicidal substituted cyclic diones ZENECA LIMITED (GB) 1988-09-21 EP disclosed
EP-0267412-A1 Imidazo-pyrrolo-pyridine derivatives BAYER AG (DE) 1988-05-18 EP disclosed
EP-0266068-A1 Herbicidal composition IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-04 EP disclosed