Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868115 | 0.86 | PNMT (0.41) | PNMTALDH1A1MAPT | |
| SCHEMBL1011335 | 0.68 | ALDH1A1 (0.52) | PNMTALDH1A1MAPT | |
| SCHEMBL18300330 | 0.67 | TAAR1 (0.35) | PNMTALDH1A1 | |
| SCHEMBL1025859 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL31564468 | 0.63 | TAAR1 (0.35) | PNMT | |
| SCHEMBL31564323 | 0.63 | PNMT (0.38) | PNMT | |
| SCHEMBL2259507 | 0.63 | PNMT (0.42) | PNMT | |
| SCHEMBL20558326 | 0.62 | MAPT (0.37) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL31564160 | 0.62 | PNMT (0.37) | PNMT | |
| SCHEMBL19454297 | 0.62 | MRGPRX2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1288203-B1 | Cyclic nitrones and pharmaceutical compositions containing them | AVENTIS PHARMA INC (US) | 2005-04-20 | — | — | EP | disclosed |
| EP-1288203-A1 | Cyclic nitrones and pharmaceutical compositions containing them | Aventis Pharmaceuticals Inc. (US) | 2003-03-05 | — | — | EP | disclosed |
| US-5962469-A | PREVENTION OF OXIDATION TISSUE DAMAGE BY FREE RADICALS | HOECHST MARION ROUSSEL INC. (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0863878-A1 | CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST MARION ROUSSEL, INC. (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010218-A1 | CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-20 | — | — | WO | disclosed |