Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099125 | 1.00 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL308119 | 0.97 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL1433752 | 0.97 | LMNA (0.48) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL3090863 | 0.95 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL2048459 | 0.95 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL16548258 | 0.95 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL8997997 | 0.95 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL16896968 | 0.95 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL3098238 | 0.93 | LMNA (0.62) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL4920668 | 0.93 | LMNA (0.62) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000432-B2 | Processes for the synthesis of chiral 1-alkanols | PURDUE RESEARCH FOUNDATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-6888030-B2 | Advances in amination | HUNTSMAN PETROCHEMICAL CORPORATION (US) | 2005-05-03 | — | — | US | disclosed |
| US-20030078344-A1 | Advances in amination | HUNTSMAN PETROCHEMICAL CORPORATION | 2003-04-24 | — | — | US | disclosed |
| US-4025649-A | INHIBITORS OF A TRANSAMINASE ENZYME, ANTIANOXIC, ANTICONVULSANT | LABAZ (FR) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000432-B2 | Processes for the synthesis of chiral 1-alkanols | CYP51A1, ALKBH3, ALKBH1 | LMNA 3812/4885SMN1; SMN2 4633/4885ALDH1A1 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.