Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 4/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382767 | 0.97 | FKBP1A (0.53) | KLK7KMT2AMEN1PREPFKBP1A | |
| SCHEMBL6172743 | 0.91 | L3MBTL1 (0.51) | KMT2APREPALDH1A1CTSLCTSK | |
| SCHEMBL27978282 | 0.88 | FKBP1A (0.52) | KMT2APREPFKBP1ACTSLCTSB | |
| SCHEMBL16030780 | 0.87 | KLK7 (0.48) | KLK7KMT2AMEN1PREPFKBP1A | |
| SCHEMBL16032213 | 0.87 | KLK7 (0.48) | KLK7KMT2AMEN1PREPFKBP1A | |
| SCHEMBL29867697 | 0.87 | KMT2A (0.45) | KLK7KMT2AFKBP1AALDH1A1GAA | |
| SCHEMBL16030781 | 0.87 | KLK7 (0.48) | KLK7KMT2AMEN1PREPFKBP1A | |
| SCHEMBL16031358 | 0.87 | KLK7 (0.48) | KLK7KMT2AMEN1PREPFKBP1A | |
| SCHEMBL30804803 | 0.87 | KLK7 (0.48) | KLK7KMT2AMEN1PREPFKBP1A | |
| SCHEMBL5241449 | 0.86 | ALDH1A1 (0.51) | KLK7KMT2AFKBP1AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546096-A1 | PROCESS FOR THE PREPARATION OF AMINO-PYRROLIDINE DERIVATIVES | Basilea Pharmaceutica AG (CH) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004013097-A1 | PROCESS FOR THE PREPARATION OF AMINO-PYRROLIDINE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2004-02-12 | — | — | WO | disclosed |