Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 5/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101734 | 0.87 | HCAR2 (0.38) | MAPTLMNAMDM4MDM2ATM | |
| SCHEMBL4661265 | 0.81 | THRB (0.50) | LMNAHCAR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7256806 | 0.75 | ATM (0.43) | MAPTATMAPPHCAR2RAB9A | |
| SCHEMBL3101738 | 0.75 | TDP1 (0.46) | LMNANPC1RAB9ASMN1; SMN2CHRM2 | |
| SCHEMBL4661596 | 0.70 | HTT (0.32) | LMNASMN1; SMN2CHRM2CHRM4CHRM1 | |
| SCHEMBL9561881 | 0.69 | ATM (0.76) | MAPTATMAPPHCAR2RAB9A | |
| SCHEMBL690840 | 0.69 | ATM (0.76) | MAPTATMAPPHCAR2RAB9A | |
| SCHEMBL690841 | 0.69 | ATM (0.76) | MAPTATMAPPHCAR2RAB9A | |
| SCHEMBL7187261 | 0.68 | HCAR2 (0.67) | MAPTLMNAHCAR2AKR1B10AKR1B1 | |
| SCHEMBL1879191 | 0.68 | HCAR2 (0.67) | MAPTLMNAHCAR2AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519968-A1 | LOW WATER CONTENT HIGH REFRACTIVE INDEX, FLEXIBLE, POLYMERIC COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2005-04-06 | — | — | EP | claimed |
| WO-2004000901-A1 | LOW WATER CONTENT HIGH REFRACTIVE INDEX, FLEXIBLE, POLYMERIC COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2003-12-31 | — | — | WO | claimed |