SCHEMBL6441695

SCHEMBL6441695

OCc1cc(Cl)nc(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDXK O00764 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
RECQL P46063 1/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30
S1PR2 O95136 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL903627 0.80 PDXK (0.42) PDXKKDM4EALDH1A1RECQLKMT2A
SCHEMBL30416243 0.78 KDM4E (0.33) PDXKKDM4EALDH1A1RECQLKMT2A
SCHEMBL13723686 0.78 ALDH1A1 (0.37) PDXKKDM4EALDH1A1RECQLKMT2A
SCHEMBL3948804 0.78 CYP2D6 (0.37) PDXKKDM4EALDH1A1RECQLKMT2A
SCHEMBL18703689 0.78 KDM4E (0.33) PDXKKDM4EALDH1A1RECQLKMT2A
SCHEMBL11001556 0.77 SMN1; SMN2 (0.34) KDM4EALDH1A1KMT2AMEN1CYP2C19
SCHEMBL31322990 0.72 TUBB4A (0.36) KDM4EALDH1A1RECQLKMT2AMEN1
SCHEMBL903616 0.71 PDXK (0.35) PDXKCYP2D6CYP2C19
SCHEMBL14671962 0.70 KDM4E (0.44) KDM4EALDH1A1KMT2AMEN1
SCHEMBL30968506 0.70 KDM4E (0.40) PDXKKDM4EALDH1A1RECQLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1203760-B1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL CO (JP) 2005-04-13 EP disclosed
US-6706910-B2 BY TRANSESTERIFICATION OF A CYCLOPROPANECARBOXYLATE AND A MONOHYDROXY COMPOUND IN THE PRESENCE OF A LITHIUM ALKOXIDE OR LITHIUM ARYLOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-16 US disclosed
EP-1203760-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-08 EP disclosed
US-20020052525-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052525-A1 Method for producing cyclopropanecarboxylates CYP8B1, SRD5A2, CYP21A2 PDXK 2152/4885KDM4E 641/4885ALDH1A1 671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.