SCHEMBL8416646

SCHEMBL8416646

C=C(C)C(=O)Oc1ccc(C(=O)O)c(C)c1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.54
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.44
KMT2A Q03164 2/20 0.43
ATM Q13315 1/20 0.43
HTT P42858 2/20 0.41
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GSTP1 P09211 2/20 0.40
RXRB P28702 2/20 0.39
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
MAPT P10636 2/20 0.38
RXRA P19793 1/20 0.38
MAPK1 P28482 1/20 0.38
ACHE P22303 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4862983 0.87 ALDH1A1 (0.59) ELANEKDM4EALDH1A1KMT2AATM
SCHEMBL6271897 0.84 ALDH1A1 (0.50) ELANEKDM4EALDH1A1KMT2AATM
SCHEMBL19888152 0.84 ELANE (0.71) ELANEKDM4EALDH1A1HTTPOLB
SCHEMBL14540336 0.84 ELANE (0.62) ELANEKDM4EALDH1A1KMT2AATM
SCHEMBL23795424 0.83 ELANE (0.51) ELANEKDM4EALDH1A1KMT2AATM
SCHEMBL30692737 0.83 ELANE (0.51) ELANEKDM4EALDH1A1KMT2AATM
SCHEMBL6441929 0.83 KDM4E (0.69) ELANEKDM4EALDH1A1HTTTDP1
SCHEMBL5323841 0.82 CFD (0.51) ELANEKDM4EALDH1A1KMT2AATM
SCHEMBL15834709 0.81 ELANE (0.50) ELANEKDM4EALDH1A1KMT2AATM
SCHEMBL7044116 0.81 ELANE (0.50) ELANEKDM4EALDH1A1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833870-B1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN AS (NO) 1999-09-08 EP claimed