Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966444 | 0.78 | GSK3B (0.51) | HIF1AALDH1A1MAOBSMN1; SMN2HPGD | |
| Ammonia Solution, Strong SCHEMBL27877917 | 0.77 | GSK3B (0.50) | HIF1AALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL21480896 | 0.76 | HIF1A (0.56) | HIF1AALDH1A1MAOBSMN1; SMN2HPGD | |
| SCHEMBL28444533 | 0.76 | HIF1A (0.43) | HIF1AALDH1A1MAOBSMN1; SMN2MAPT | |
| SCHEMBL4620050 | 0.76 | MAPT (0.44) | HIF1AALDH1A1MAOBSMN1; SMN2HPGD | |
| SCHEMBL28488601 | 0.76 | RORC (0.47) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL30139082 | 0.76 | KCNQ2 (0.54) | HIF1ATSHRALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL4411118 | 0.75 | RORC (0.46) | TSHRALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL13005154 | 0.75 | MAPT (0.61) | ALDH1A1MAOBSMN1; SMN2HPGDMAPT | |
| SCHEMBL25062239 | 0.75 | LMNA (0.57) | HIF1ATSHRALDH1A1MAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567518-A2 | OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS | Ciba SC Holding AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050653-A2 | OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-06-17 | — | — | WO | disclosed |