SCHEMBL6441998

SCHEMBL6441998

C=C(CCc1cccc(OC)c1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
CTBP2 P56545 1/20 0.54
HDAC1 Q13547 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
RAB9A P51151 1/20 0.53
TAAR1 Q96RJ0 1/20 0.53
MTNR1A P48039 2/20 0.52
MTNR1B P49286 2/20 0.52
CYP1A2 P05177 1/20 0.51
GAA P10253 1/20 0.51
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
TDP1 Q9NUW8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1621499 0.91 HDAC1 (0.58) MEN1KMT2ACTBP2HDAC1HDAC6
SCHEMBL16932501 0.85 FFAR1 (0.56) TDP1
SCHEMBL17940816 0.85 ERCC5 (0.51) RAB9AKDM4EALDH1A1
SCHEMBL7293162 0.84 CTBP2 (0.64) MEN1KMT2ACTBP2RAB9AMTNR1A
SCHEMBL346302 0.84 FFAR1 (0.65) HDAC1HDAC6RAB9ATAAR1MTNR1A
SCHEMBL7561923 0.83 MEN1 (0.49) MEN1KMT2ACTBP2CYP1A2GAA
SCHEMBL17940825 0.82 FFAR1 (0.43) KMT2ARAB9ATDP1
SCHEMBL7332474 0.82 TAAR1 (0.61) HDAC1HDAC6RAB9ATAAR1MTNR1A
SCHEMBL268552 0.81 RAB9A (0.69) HDAC1HDAC6RAB9ATAAR1MTNR1A
SCHEMBL1921185 0.81 F2RL1 (0.62) MEN1KMT2ARAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1015505-B1 PRODUCTION OF PHOTOPOLYMERIZED POLYESTER HIGH INDEX OPHTHALMIC LENSES SIGNET ARMORLITE INC (US) 2005-03-09 EP claimed
EP-0783710-B1 POLYESTER RESIN-BASED HIGH INDEX OPHTHALMIC LENSES HAVING IMPROVED OPTICAL UNIFORMITY AND/OR TINTABILITY SIGNET ARMORLITE INC (US) 2002-05-29 EP claimed
EP-3191590-B1 SORBENT MATERIAL FOR SEPARATING BIO-MACROMOLECULES QUANTUMDX GROUP LTD (GB) 2024-02-21 EP disclosed
US-10792640-B2 Sorbent material for separating bio-macromolecules QUANTUMDX GROUP LIMITED (GB) 2020-10-06 US disclosed
US-20170282154-A1 SORBENT MATERIAL FOR SEPARATING BIO-MACROMOLECULES QUANTUMDX GROUP LIMITED (GB) 2017-10-05 US disclosed
EP-3191590-A1 SORBENT MATERIAL FOR SEPARATING BIO-MACROMOLECULES Quantumdx Group Limited (GB) 2017-07-19 EP disclosed
WO-2016040697-A1 SORBENT MATERIAL FOR SEPARATING BIO-MACROMOLECULES QUANTUMDX GROUP LIMITED (GB) 2016-03-17 WO disclosed