Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL3262300 | 0.92 | DAO (0.52) | KMT2ASRD5A2TSHRPTGESALOX5 | |
| Terephthalic Acid SCHEMBL31485057 | 0.90 | TSHR (0.55) | KMT2ASRD5A2TP53TSHR | |
| Terephthalic Acid SCHEMBL87786 | 0.90 | TSHR (0.55) | KMT2ASRD5A2TP53TSHR | |
| SCHEMBL10939284 | 0.87 | KMT2A (0.46) | KMT2ASRD5A2TSHRPTGESALOX5 | |
| Terephthalic Acid SCHEMBL6557198 | 0.86 | KMT2A (0.46) | KMT2ASRD5A2TP53TSHRNPSR1 | |
| Terephthalic Acid SCHEMBL2206532 | 0.86 | TSHR (0.50) | KMT2ASRD5A2TP53TSHR | |
| Terephthalic Acid SCHEMBL28820897 | 0.86 | TSHR (0.50) | KMT2ASRD5A2TP53TSHR | |
| Terephthalic Acid SCHEMBL27707378 | 0.86 | TSHR (0.50) | KMT2ASRD5A2TP53TSHR | |
| Terephthalic Acid SCHEMBL7753889 | 0.82 | TSHR (0.50) | KMT2ASRD5A2TP53TSHRNPSR1 | |
| Benzoic Acid SCHEMBL17797781 | 0.82 | TSHR (0.58) | KMT2ASRD5A2TP53TSHRKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715560-B | Organic oxygroup acid imide is used as the purposes of radical-forming agent in the plastic, generates the method for free radical and the purposes of this method | 弗劳恩霍弗应用研究促进协会 | 2019-08-27 | — | — | CN | claimed |
| CN-107001688-A | Polymer composition with delayed crystallisation behavior, influence crystallization behavior compositions of additives, reduction crystalline temperature and/or crystallization rate method and the purposes of compositions of additives | 弗劳恩霍夫应用研究促进协会 | 2017-08-01 | — | — | CN | claimed |
| CN-102731566-A | Alkyl phosphinate polymer as well as preparation method and application thereof | SHANGHAI HUIHAI CHEMICAL TECHNOLOGY CO LTD | 2012-10-17 | — | — | CN | claimed |
| US-20030175499-A1 | Compositions for imparting a translucent optical effect to transparent thermoplastic polymers | U.S. BANK TRUST NATIONAL ASSOCIATION, AS SUCCESSOR CORPORATE TRUSTEE TO STATE STREET BANK AND TRUST COMPANY, N.A. | 2003-09-18 | — | — | US | claimed |
| WO-1998056850-A1 | CONCENTRATE COMPOSITIONS FOR IMPARTING A TRANSLUCENT OPTICAL EFFECT TO TRANSPARENT THERMOPLASTIC POLYMERS | M.A. HANNACOLOR (US) | 1998-12-17 | — | — | WO | claimed |
| CN-106574090-B | 3- phenylbenzofuran -2- ketone diphosphorous acid ester derivant as stabilizer | 巴斯夫欧洲公司 | 2019-11-19 | — | — | CN | disclosed |
| CN-106459255-B | Oxygen-containing imide copolymer or high molecular polymer as flame retardant for plastic material | 弗劳恩霍夫应用研究促进协会 | 2019-11-05 | — | — | CN | disclosed |
| CN-106715560-B | Organic oxygroup acid imide is used as the purposes of radical-forming agent in the plastic, generates the method for free radical and the purposes of this method | 弗劳恩霍弗应用研究促进协会 | 2019-08-27 | — | — | CN | disclosed |
| CN-106211777-B | The seven phosphorus derivative compounds as fire retardant | 巴斯夫欧洲公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-109642049-A | Additive agent mixture | 巴斯夫欧洲公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-105399730-B | Sterically hindered amine stabilizer | 巴斯夫欧洲公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-103992566-B | With the polymer composition for improving resistance to scraping, improvement mechanical stability and improvement mist degree | 巴斯夫欧洲公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-1091118-A | α, ω-alkane bis-phenol | CIBA GEIGY AG (CH) | 1994-08-24 | — | — | CN | disclosed |
| CN-1090588-A | The plastic molded material of using for the decoration moulded piece of making color tunable | HOECHST AG (DE) | 1994-08-10 | — | — | CN | disclosed |
| CN-1077448-A | Carboxylicesters as the hydroxyphenylalkanolas of stablizer | CIBA GEIGY AG (CH) | 1993-10-20 | — | — | CN | disclosed |
| CN-1043728-A | Water-soluble cpds as photostabilizer | CIBA GEIGY AG (CH) | 1990-07-11 | — | — | CN | disclosed |
| CN-1037337-A | Substituted 2H-benzotriazole liquid mixtures | CIBA GEIGY AG (CH) | 1989-11-22 | — | — | CN | disclosed |
| EP-0243319-A2 | Thermoplastics stabilized against the influence of light | CIBA-GEIGY AG (CH) | 1987-10-28 | — | — | EP | disclosed |
| EP-0240463-A2 | Substituted aminooxypropion amides | CIBA-GEIGY AG (CH) | 1987-10-07 | — | — | EP | disclosed |
| EP-0140298-A1 | Substituted 4-hydroxybenzylthioaldehydes and ketones | CIBA-GEIGY AG (CH) | 1985-05-08 | — | — | EP | disclosed |