Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | BLM | P54132 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 13/20 | 0.41 |
| ▸ | MAPT | P10636 | 13/20 | 0.41 |
| ▸ | GAA | P10253 | 12/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PLEC | Q15149 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199390 | 0.88 | RAD52 (0.52) | ALDH1A1BLMPOLBKMT2ARAD52 | |
| SCHEMBL29412557 | 0.88 | RAD52 (0.52) | ALDH1A1BLMPOLBKMT2ARAD52 | |
| SCHEMBL315397 | 0.70 | RAD52 (0.52) | ALDH1A1BLMPOLBKMT2ARAD52 | |
| SCHEMBL7537819 | 0.69 | ALDH1A1 (0.43) | ALDH1A1BLMPOLBKMT2AGAA | |
| Urea SCHEMBL27809106 | 0.68 | ALDH1A1 (0.52) | ALDH1A1POLBKMT2AMEN1GAA | |
| Urea SCHEMBL15757519 | 0.68 | ALDH1A1 (0.52) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL14559393 | 0.66 | ACVR1 (0.52) | KMT2AMEN1MAPTGAANPC1 | |
| SCHEMBL157601 | 0.66 | KDM4E (0.55) | ALDH1A1POLBMAPTGAAKDM4E | |
| SCHEMBL4155254 | 0.66 | RAD52 (0.52) | ALDH1A1BLMPOLBKMT2ARAD52 | |
| SCHEMBL27660778 | 0.66 | GAA (0.57) | ALDH1A1BLMPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1579207-A2 | MEASUREMENT OF TOTAL REACTIVE ISOCYANATE GROUPS IN SAMPLES USING BIFUNCTIONAL NUCLEOPHILES SUCH AS 1,8-DIAMINONAPHTHALENE (DAN) | The Government of the United States of America, as represented by the Secretary, Department of Health & Human Services (US) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004051221-A2 | MEASUREMENT OF TOTAL REACTIVE ISOCYANATE GROUPS IN SAMPLES USING BIFUNCTIONAL NUCLEOPHILES SUCH AS 1,8-DIAMINONAPHTHALENE (DAN) | THE GOVERNMENT OF THE UNITED STATES OF AMERICA (US) | 2004-06-17 | — | — | WO | disclosed |